Peroxisomal proliferator-activated receptor gamma (PPARγ) is a nuclear hormone receptor whose agonist, rosiglitazone has a neuroprotective effect to hippocampal neurons in pilocarpine-induced seizures.Hippocampal slice preparations treated in Mg2+ free medium can induce ictal and interictal-like epileptiform discharges, which is regarded as an in
The new frontiers of sustainable cities should focus on urban planning tools and strategies that are able to integrate ecosystem services in urban development.An important step could include the design of nature-based solutions (NbSs) for introducing important ecological functions aiding human well-being and mitigating the loss of soil.In this stud
Lauren E Friedman,1 Ana Karen Manriquez Prado,2,* Gabriel Fidel Santos Malavé,2,* Juan Carlos Vélez,3 Rodrigo Winston Gillibrand Esquinazi,4 Sixto E Sanchez,5,6 Qiu-Yue Zhong,1 Bizu Gelaye,1 Michelle A Williams1 1Department of Epidemiology, Harvard T.H.Chan School of Public Health, Boston, MA, USA; 2Multidisciplinary International Res
Non-judicious antimicrobial use (AMU) is a major driver of antimicrobial resistance (AMR).In human hospitals, cumulative antibiograms are often used by clinicians to evaluate local susceptibility rates and to select the most appropriate empiric therapy with the aim of minimizing inappropriate AMU.However, drive set the use of cumulative antibiogram